Quantification of PRL/Stat5 signaling with a novel pGL4-CISH reporter
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چکیده
منابع مشابه
Quantification of PRL/Stat5 signaling with a novel pGL4-CISH reporter
BACKGROUND Elevations of serum prolactin (PRL) are associated with an increased risk for breast cancer. PRL signaling through its prolactin receptor (PRLr) involves the Jak2/Stat5 pathway. Luciferase-based reporter assays have been widely used to evaluate the activity of this pathway. However, the existing reporters are often not sensitive enough to monitor the effect of PRL in this pathway. ...
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ژورنال
عنوان ژورنال: BMC Biotechnology
سال: 2008
ISSN: 1472-6750
DOI: 10.1186/1472-6750-8-11